Abstract: Objective To investigate the associations of occupational, educational and residential factors with the outcomes of in
vitro fertilization -embryo transfer (IVF-ET). Methods A retrospective analysis was conducted among 3998 patients undergoing
the first treatment with IVF-ET and 3064 perinatal infants in our center between January, 2010 and June, 2014. The relation of
the patients’ occupation, educational background, and residence registry with IVF-ET outcomes was analyzed. Results The
risk of abortion in the first trimester was significantly higher in female patients engaged in agriculture (OR=4.319, P=0.047).
Occupation and educational background of the patients and their spouse were related with the incidence of ectopic pregnancy
following IVF-ET. The total incidence rate of perinatal birth defects was 2.1% in this cohort, and was the highest in Shenzhen
(5.5% ) but this difference was not statistically significant (P>0.05). Conclusion The patients’ occupation and educational
background are related with the outcomes of IVF-ET, suggesting the importance of health education and prenatal examination.