Abstract: Objective To study the correlation between adipocytokines levels and metabolic syndrome (MS) in patients with
newly diagnosed type 2 diabetes mellitus (T2DM). Methods Sixty-eight patients with newly diagnosed T2DM, including 51
cases with MS and 17 without MS, were examined for blood pressure (BP), fasting blood glucose (FBG), fasting insulin (FINS),
insulin resistance index (IRI), waist to hip ratio (W/H), body mass index (BMI), and serum dipocytokine levels (IL-6, vaspin,
and adiponectin). Results The diabeitc patients with MS had higher BMI, HbA1c, FBG, FINS, IRI, TG, TC, and SBP than those
without MS. Serum IL-6 level was higher but adiponectin level was lower in patients with MS than in those without MS. There
was no significant difference in vispin level between the two groups. Adiponectin level was positively correlated with TG
(r=-0.30, P=0.02) and inversely with BMI (r=-0.47, P=0.39) and HOMA-IR (r=-0.30, P=0.03); vispin level was positively correlated
with HOMA-IR (r=0.347, P=0.02) and inversely with HDL-L (r=-0.45, P=0.01); IL-6 level was positively correlated with LDL-L
(r=0.18, P=0.25) and inversely with HDL-L (r=-0.45, P=0.01). Conclusion Adiponectin and IL-6 levels are closely related to MS,
but the relationship between vispin and MS needs further invesitgation.