Abstract: Hemoptysis is a common complication of bronchiectasis, but concurrent primary hyperfibrolysis is very rare and
easily gives rise to missed diagnosis. Patients with bronchiectasis complicated by primary hyperfibrolysis do not respond to
regular treatment for hemoptysis, which may potential cause fatal consequences. We report two cases of bronchiectasis
combined with primary hyperfibrinolysis. Both of the patients had a history of bronchiectasis and were admitted for
intermittent hemoptysis. Conventional treatment such as vasopressin failed to produce a favorable response. The eventual
definite diagnosis of primary hyperfibrinolysis was established based on laboratory examinations. After diagnosis, the patients
received fibrinogen and cryoglobulin to maintain a fibrinogen level over1.5g/L. Both of the patients subsequently showed
improved conditions and were discharged.