Abstract: ObjectiveDeuterium is an important predisposing factor for cancer. Deuterium-depleted Water, also known as low
deuterium water, ultra-light water or no deuterium water, can be obtained by removing deuterium from natural water. Studies
have shown that water with a low deuterium concentration (<65% percent of volume) can inhibit cancer growth. Clinical trials
demonstrated that drinking DDW (10-20ppm) caused growth arrest of malignant cells in cancer patients and significantly
prolonged the patient survival with also improved quality of life. A wide range of anti-cancer drugs in current use are
associated with severe adverse effects, while deuterium-depleted water appears to have virtually no pharmacological side
effects and is convenient to administer. The authors review the advances in the researches of anti-cancer effects and the
underlying mechanisms of deuterium-depleted water.