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javax.script.AbstractScriptEngine.eval(java.lang.String,javax.script.Bindings) throws javax.script.ScriptException public java.lang.Object javax.script.AbstractScriptEngine.eval(java.io.Reader) throws javax.script.ScriptException public java.lang.Object javax.script.AbstractScriptEngine.eval(java.lang.String) throws javax.script.ScriptException public java.lang.Object javax.script.AbstractScriptEngine.eval(java.io.Reader,javax.script.Bindings) throws javax.script.ScriptException public void javax.script.AbstractScriptEngine.setContext(javax.script.ScriptContext) public javax.script.Bindings javax.script.AbstractScriptEngine.getBindings(int) public void javax.script.AbstractScriptEngine.setBindings(javax.script.Bindings,int) public final void java.lang.Object.wait() throws java.lang.InterruptedException public final void java.lang.Object.wait(long,int) throws java.lang.InterruptedException public final native void java.lang.Object.wait(long) throws java.lang.InterruptedException public 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Journal of Southern Medical University ›› 2006, Vol. 26 ›› Issue (02): 189-192.

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Effects of Buyanghuanwu decoction on nerve proliferation in rats with sequelae of ischemic stroke

TAN Xian-hui, QU Hong-da, PENG Kang, CHEN Yu-yao, TONG Li, SHEN Jian-gang, ZHU Chuan-wu College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China; School of Traditional Chinese Medicine, Chinese University of Hong Kong, Hong Kong, China   

  1. 南方医科大学中医药学院； 香港中文大学中医药学院； 南方医科大学中医药学院 广东广州510515； 广东广州510515； 香港沙田；
  • Online:2006-02-20 Published:2006-02-20

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Abstract: Objective To examine the effect of Buyanghuanwu decoction (BYHWD) in inducing nerve proliferation in rats with sequelae of ischemic stroke. Methods A rat model of ischemic stroke sequelae was established by means of craniectomy in which the right common carotid artery was ligated with 4-0 silk thread followed by cauterization of the right middle cerebral-artery. Programmed electric shock was administered 24 h after the onset of ischemic stroke for 2 h daily for 20 consecutive days. The rats in sham operation group were not subjected to ligation of the right common carotid artery or right middle cerebral artery occlusion. The rats in the treatment groups were given oral BYHWD for 15 consecutive days. All the rats received repeated intraperitoneal injections of the cell proliferation-specific marker 5-bromodeoxyuridine (BrdU), and the intake of Br-dU in the cerebral tissues was determined by immunohistochemistry. Results The number of BrdU-immunoreactive cells in the cerebral tissues of BYHWD-treated rats was significantly greater than that in the untreated model group. Conclusion BYHWD can promote nerve proliferation in rats with ischemic stroke sequelae.

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