[1] Lee SY. High cell-density culture ofEscherichia coli [J]. Trends Biotechnol, 1996, 14(3): 98-105. [2] Makrides SC. Strategies for achieving high-level expression of genes in Escherichia coli[J]. Microbiol Rev, 1996, 60(3): 512-38. [3] 李仲宏,麦国丰,罗荣城,等.瘤内注射核素标记混合抗体治疗肝癌的实验研究[J].第一军医大学学报,2000,20(4):327-8.Li ZH, Mai GF, Luo RC, et al. Experimental studies of treatment of the liver cancer by intratumoral injection of 131I-labeled multiple monoclonal antibodies [J]. J First Mil Med Univ/Di Yi Jun Yi Da Xue Xue Bao, 2000, 20(4): 327-8. [4] 罗荣城,尤长宣,韩焕兴,等.人源乙型肝炎病毒表面抗原抗体Fab片段与IFN-α融合蛋白表达载体的筛选[J].第一军医大学学报,2000,20(2):100-3.Luo RC, You CX, Han HX, et al. Selection of the expression vector for the fusion protein of human anti-HBs antibody Fab fragment and interferon-α [J]. J First Mil Med Univ/Di Yi Jun Yi Da Xue Xue Bao, 2000, 20(2): 100-3. [5] Riesenberg D, Menzel K, Schulz V, et al. High-cell density fermentation of recombinant Escherichia coli. Expressing human interferon alpha[J]. Appl Microbio Biotechnol, 34(1): 77-82. [6] Pluckthun A, Krebber A. Producing antibodies in Escherichia coli:from PCR to fermentation [A]. In: McCaffergy J, Hoogenboon H,Chiswell D, eds. Antibody Engineering: A Practical Approach [M].Oxford: Oxford University Press, 2001. 203-52. [7] Luli GW, Strohl WR. Comparison of growth, acetate, production and acetate inhibition of Escherichia coli. Strains in batch and fedbatch fermentation[J]. Appl Environ Microbiol, 1990, 56(4): 1004-11. [8] Guzman LM, Belin D, Carso MJ, et al. Tight regulation, modulation,and high-level expression by vectors containing the arabinose pBAD promoter[J]. J Bacteriol, 177(54): 4121-30. [9] Horn V, Strittmatter W. High volumetric yields of functional dimeric miniantibodies in Escherichia coli. Using an optimized expression vector and high-cell-density fermentation under non-limited growth conditions[J]. Appl Microbiol Biotechnol, 46(3): 524-32. [10] Clark MA, Hammond FR, Papaioannou A, et al. Regulation and expression of human Fab under the control of the Escherichia coli arabinose promoter, pBAD [J]. Immunotechnology, 1997, 3 (3): 217-26. |