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吕雪彩, 刘艳红, 韩诗怡, 张浩赟, 侯爱生, 周志康, 史立凯, 高洁, 曹江北, 张宏, 米卫东
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Xuecai LÜ, Yanhong LIU, Shiyi HAN, Haoyun ZHANG, Aisheng HOU, Zhikang ZHOU, Likai SHI, Jie GAO, Jiangbei CAO, Hong ZHANG, Weidong MI
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| Parameter | Total (n=1388) | No postoperative complications (n=683) | Have postoperative complications (n=705) | OR (95% CI) | P |
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| Age (year) | 71.0 (68.0, 76.0) | 71.0 (68.0, 75.0) | 72.0 (68.0, 76.0) | 1.028 (1.008-1.048) | 0.005 | | Gender [n (%)] | | | | 1.002 (0.804-1.250) | 0.984 | | Female | 906 (65.3%) | 446 (65.3%) | 460 (65.2%) | | | | Male | 482 (34.7%) | 237 (34.7%) | 245 (34.8%) | | | | Height (cm) | 164.6 (160.0, 170.0) | 165.0 (160.0, 170.0) | 164.6 (160.0, 170.0) | 1.001 (0.998-1.014) | 0.884 | | Weight (kg) | 63.7 (57.0, 70.0) | 63.7 (57.0, 70.0) | 63.7 (57.0, 70.0) | 0.997 (0.987-1.007) | 0.541 | | BMI (kg/m2) | 23.5 (21.3, 25.4) | 23.5 (21.3, 25.6) | 23.5 (21.4, 25.1) | 0.985 (0.953-1.018) | 0.374 | | ASA | | | | 1.262 (1.001-1.590) | 0.049 | | Ⅰ-Ⅱ | 978 (70.5%) | 498 (72.9%) | 480 (68.1%) | | | | Ⅲ-Ⅴ | 410 (29.5%) | 185 (27.1%) | 225 (31.9%) | | | | Medical History [n (%)] | | | | | | | Hypertension | 605 (43.6%) | 289 (42.3%) | 316 (44.8%) | 1.107 (0.896-1.369) | 0.346 | | Diabetes | 290 (20.9%) | 131 (19.2%) | 159 (22.6%) | 1.227 (0.946-1.591) | 0.123 | | Coronary heart disease | 188 (13.5%) | 88 (12.9%) | 100 (14.2%) | 1.118 (0.821-1.521) | 0.479 | | Cerebrovascular disease | 79 (5.7%) | 31 (4.5%) | 48 (6.8%) | 1.537 (0.966-2.445) | 0.070 | | Respiratory disease | 55 (4.0%) | 21 (3.1%) | 34 (4.8%) | 1.597 (0.917-2.781) | 0.098 | | Kidney disease | 66 (4.8%) | 29 (4.2%) | 37 (5.2%) | 1.249 (0.759-2.055) | 0.381 | | Smoking | 432 (31.1%) | 218 (31.9%) | 214 (30.4%) | 0.930 (0.741-1.167) | 0.529 | | Alcohol consumption | 410 (29.5%) | 207 (30.3%) | 203 (28.8%) | 0.930 (0.738-1.171) | 0.537 | | Preoperative chronic pain | 255 (18.4%) | 106 (15.5%) | 149 (21.1%) | 1.459 (1.108-1.920) | 0.007 | | Preoperative nutritional support | 163 (11.7%) | 71 (10.4%) | 92 (13.0%) | 1.294 (0.931-1.798) | 0.125 | | Preoperative psychological and functional status | | | | | | | Frailty [n (%)] | 35 (2.5%) | 14 (2.0%) | 21 (3.0%) | 1.467 (0.740-2.909) | 0.272 | | EQ-5D | 1.0 (0.9, 1.0) | 1.0 (0.9, 1.0) | 0.9 (0.9, 1.0) | 0.073 (0.014-0.380) | 0.002 | | EQ-VAS | 76.0 (70.0, 80.0) | 76.0 (75.0, 80.0) | 76.0 (70.0, 80.0) | 0.992 (0.984-1.000) | 0.060 | | MET | | | | 0.719 (0.483-1.070) | 0.104 | | <4 | 108 (7.8%) | 45 (6.6%) | 63 (8.9%) | | | | ≥4 | 1280 (92.2%) | 638 (93.4%) | 642 (91.1%) | | | | Preoperative laboratory test | | | | | | | PNI | 42.3 (37.4, 126.3) | 42.9 (38.1, 139.0) | 41.7 (36.8, 89.5) | 0.998 (0.997-1.000) | 0.043 | | Albumin (g/L) | 39.0 (36.2, 41.2) | 39.0 (36.5, 41.0) | 39.0 (36.0, 41.3) | 0.995 (0.984-1.006) | 0.401 | | Hemoglobin (g/L) | 120.6 (108.0, 134.0) | 122.0 (109.0, 135.0) | 120.3 (106.0, 134.0) | 0.996 (0.991-1.001) | 0.120 | | Glucose (µmol/L) | 5.5 (4.8, 5.8) | 5.5 (4.8, 5.8) | 5.5 (4.8, 5.8) | 1.021 (0.956-1.091) | 0.531 | | Intraoperative medication | | | | | | | Consumption of opioids (mg) | 143.5 (50.0, 232.9) | 140.0 (50.0, 230.0) | 148.0 (45.0, 240.0) | 1.000 (0.999-1.001) | 0.796 | | NSAIDs [n (%)] | 529 (38.1%) | 264 (38.7%) | 265 (37.6%) | 0.956 (0.770-1.187) | 0.683 | | Dexmedetomidine [n (%)] | 333 (24.0%) | 174 (25.5%) | 159 (22.6%) | 0.852 (0.666-1.090) | 0.203 | | Surgical/Anesthetic parameters | | | | | | | Blood loss (mL) | 100.0 (50.0, 128.7) | 60.0 (50.0, 128.7) | 100.0 (50.0, 128.7) | 1.002 (1.001-1.003) | <0.001 | | Duration of surgery (min) | 191.5 (143.3, 240.0) | 185.0 (136.0, 230.0) | 198.4 (150.0, 250.0) | 1.002 (1.001-1.003) | 0.002 | | Location of surgery [n (%)] | | | | 0.930 (0.746-1.160) | 0.521 | | Gastrectomy | 481 (34.7%) | 231 (33.8%) | 250 (35.5%) | | | | Enterectomy | 907 (65.3%) | 452 (66.2%) | 455 (64.5%) | | | | Type of surgery [n (%)] | | | | 1.194 (0.934-1.527) | 0.157 | | Open | 1050 (75.6%) | 528 (77.3%) | 522 (74.0%) | | | | Minimally invasive | 338 (24.4%) | 155 (22.7%) | 183 (26.0%) | | | | Anesthesia methods [n (%)] | | | | 0.843 (0.621-1.145) | 0.275 | | GA | 1197 (86.2%) | 582 (85.2%) | 615 (87.2%) | | | | GA+RA | 191 (13.8%) | 101 (14.8%) | 90 (12.8%) | | | | Postoperative analgesia methods [n (%)] | | | | | 0.191 | | No | 480 (34.6%) | 286 (36.5%) | 194 (34.6%) | | | | Intravenous analgesia | 784 (56.5%) | 432 (55.2%) | 352 (56.5%) | 1.201 (0.954, 1.512) | | | Others | 124 (8.9%) | 65 (8.3%) | 59 (9.8%) | 1.338 (0.900, 1.990) | | | Postoperative acute pain | | | | 1.359 (1.079-1.712) | 0.009 | | Mild to moderate pain | 973 (70.1%) | 501 (73.4%) | 472 (67.0%) | | | | Severe pain | 415 (29.9%) | 182 (26.6%) | 233 (33.0%) | | |
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