Abstract: Objective To compare the perioperative, functional and oncologic outcomes of patients with prostate cancer receiving
laparoscopic radical prostatectomy (LRP) using three-dimensional (3D) versus two-dimensional (2D) imaging systems. Methods
From February, 2014 to January 2016, 72 consecutive patients with clinically localized prostate cancer underwent LRP with 2D or
3D imaging systems performed by a single experienced surgeon. The baseline characteristics, perioperative data, and functional
and oncologic outcomes of the patients were collected and analyzed. Results Thirty-six patients underwent 3D LRP and the
other 36 patients underwent 2D LRP. Compared with 2D LRP group, 3D LRP group had a significantly shorter operative time
(167 vs 218 min, P<0.001), a smaller volume of intraoperative blood loss (86.11 vs 177.78 mL, P<0.001) and a better early urinary
continence outcome (88.89% vs 63.89%, P=0.026). No significant differences were found between the two groups in terms of
complications, potency outcome or biochemical recurrence-free rate. Conclusion Compared with 2D LRP, 3D LRP shortens the
operative time, reduces intraoperative blood loss and is associated with a better early urinary continence outcome in patients
with clinically localized prostate cancer.