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Journal of Southern Medical University ›› 2015, Vol. 35 ›› Issue (10): 1515-.

Previous Articles    

Intensive hemoperfusion and long-term hemofiltration for treatment of paraquat
poisoning: a case report

  

  • Online:2015-10-20 Published:2015-10-20

PDF

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Abstract: A 20-year-old male patient was admitted in our department 14 h after paraquat poisoning at the dose of about 50 mL.
The patient underwent intensive hemoperfusion for 2 h (3 times a day) for 9 consecutive days and received continuous renal
replacement therapy (CRRT) in the mode of continuous veno-venous hemofiltration (CVVH) for 10 consecutive days in
addition to routine medications. The biochemical indexes were monitored during the therapy. After the treatment, paraquat
concentrations in the blood and urine were decreased, and the patient’s urine volume (UV) increased, serum creatinine (Cr)
level decreased, and the oxygenation index became normal. Dynamic CT scan showed no obvious pulmonary fibrosis. The
patient was followed up for 6 months after discharge and no complaint of discomforts was reported. This case suggests that
early intensive hemoperfusion and long-term CVVH may help improve the prognosis after paraquat poisoning.