Abstract: Recently the studies on mosquito genomics, transcriptomics and small RNAomics developed rapidly with the novel
biotechnologies of the next generation sequencing techniques. The genome sequences of several important vector mosquitoes
including Anopheles gambiae, Culex quinquefasciatus, and Aedes aegypti have been published. The genome sizes vary among the
different species of mosquitoes and are consistent with the number of the repeat regions. The released genome sequences
facilitate gene cloning and identification as for OBP, OR and dsx genes. Transcriptomics provides a useful tool for functional
analyses of the mosquito genes, and using this technique, the molecular basis of mosquito blooding, gland proteins and
diapauses have been explored. Studies on small RNAomics suggest important roles of miRNAs and piRNAs in ovary
development, blood digestion, and immunity against virus infection. The studies on mosquito omics have generated a big data
platform for investigation of vector biology and vector-transmitted disease prevention.