[1]纪雪霞,周国斌,王庆,等.低剂量舒芬太尼联合腹横肌平面阻滞术后镇痛可加速腹腔镜全子宫切除患者的康复[J].南方医科大学学报,2019,(03):369.[doi:10.12122/j.issn.1673-4254.2019.03.17]
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低剂量舒芬太尼联合腹横肌平面阻滞术后镇痛可加速腹腔镜全子宫切除患者的康复()
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《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2019年03期
页码:
369
栏目:
出版日期:
2019-04-11

文章信息/Info

Title:
Postoperative low-dose sufentanil combined with transversus abdominis plane block promotes recovery following laparoscopic hysterectomy
作者:
纪雪霞周国斌王庆孙强马珏王晟
关键词:
加速康复外科术后镇痛腹横肌平面阻滞舒芬太尼
Keywords:
laparoscopic hysterectomy postoperative recovery postoperative analgesia transversus abdominis plane block low-dose sufentanil
DOI:
10.12122/j.issn.1673-4254.2019.03.17
摘要:
目的探讨有利于腹腔镜全子宫切除术患者快速康复的镇痛措施。方法选择2016年9月~2017年8月广东省人民医院收 治的腹腔镜全子宫切除术患者60例,ASA Ⅰ~Ⅱ级,年龄25~55岁,随机分为两组,每组30例。A组为舒芬太尼1 μg/kg+甲磺酸 托烷司琼9.96 mg+凯纷200 mg+0.9%氯化钠溶液稀释至100 mL联合超声引导双侧脐平面腹横肌平面(TAP)阻滞;B组为舒芬 太尼2 μg/kg+甲磺酸托烷司琼9.96 mg+凯纷200 mg+0.9%氯化钠溶液稀释至100 mL,维持速度均为2 mL/h。采用视觉模拟评 分法(VAS评分)评估术后15 min、4、8、12、24、48 h疼痛程度,记录术后首次下床时间、术后住院时间和恶心呕吐发生率。结果 与B组相比,A组患者术后15 min、4、8、12 h VAS评分均降低,差异有统计学意义(P<0.01)。同时,与B组相比,A组患者术后首 次下床时间和住院时间也显著缩短,差异有统计学意义(P<0.01)。A组2例患者术后出现轻度恶心、呕吐反应,发生率6.67%。 B组6例患者术后出现恶心、呕吐反应,发生率20.00%。其中4例患者轻度恶心呕吐,2例患者中度恶心呕吐。结论1 μg/kg舒 芬太尼联合TAP阻滞在腹腔镜全子宫切除术后镇痛效果可靠,同时降低恶心、呕吐发生率,缩短术后首次下床时间和住院时间, 有利于加速患者快速康复。
Abstract:
Objective To compare the efficacy and safety of postoperative analgesia with low- dose sufentanil combined with transversus abdominis plane (TAP) block and with sufentanil alone in promoting patients’recovery following laparoscopic hysterectomy. Methods Sixty patients undergoing laparoscopic hysterectomy in our hospital between September, 2016 and August, 2017 were randomly allocated into two equal groups. In group A, the patients were given postoperative analgesia with 1 μg/kg sufentanil, 9.96 mg tropisetronmesylate, and 200 mg flurbiprofen axetil (diluted with 0.9% NaCl solution to 100 mL, pumped at the rate of 2 mL/h) combined with TAP block; in group B, the patients received similar postoperative analgesia but at a higher dose of sufentanil (2 μg/kg) without TAP block. Visual analogue scale (VAS) was used to evaluate pain at 15 min and at 4, 8, 12, 24 and 48 h postoperatively, and the first off-bed time, the length of postoperative hospital stay and the incidence of postoperative nausea and vomiting (PONV) were recorded in all the patients. Results Compared with those in group B, the patients in group A had significantly lower VAS scores at 15 min, 4 h, 8 h, and 12 h postoperatively (P< 0.01) with also statistically shorter first off-bed time and postoperative hospital stay (P<0.01). Two (6.7%) patients in group A had mild PONV, and 6 (20.0%) in group B had PONV (including 4 with mild and 2 with moderate PONV). Conclusion Lowdose sufentanil combined with TAP block is effective for postoperative analgesia after laparoscopic hysterectomy and helps to reduce the incidence of PONV and shorten the first off-bed time and postoperative hospital stay to promote the recovery of the patients.
更新日期/Last Update: 1900-01-01