[1]元龚骏,郑小康,朱晓霞,等.鼻咽癌Ⅰb区淋巴结肿大的相关因素分析[J].南方医科大学学报,2014,(07):983.
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鼻咽癌Ⅰb区淋巴结肿大的相关因素分析()
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《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2014年07期
页码:
983
栏目:
出版日期:
2014-07-15

文章信息/Info

Title:
Risk factors of level Ib lymphadenopathy in nasopharyngeal carcinoma
作者:
元龚骏郑小康朱晓霞王哲宋文张弘沙舟
关键词:
鼻咽肿瘤淋巴结转移放射治疗口腔干燥症
Keywords:
nasopharyngeal neoplasms lymph node metastasis radiotherapy xerostomia
摘要:
目的回顾性分析鼻咽癌各种临床因素与Ⅰb区淋巴结肿大的相关性,为确定鼻咽癌Ⅰb区预防照射指征提供参考。方法
选取近3年来在南方医院诊断为鼻咽癌的初治患者影像资料435例,研究其T分期、N分期、Ⅱ区肿大淋巴结直径、下颌下腺侵
犯、鼻腔侵犯、口咽侵犯、≥4个淋巴结引流区转移等临床高危因素与ⅠB区淋巴结肿大的相关关系。结果单因素分析显示N分
期(P=0.023)、下颌下腺侵犯(P=0.045)、Ⅱ区淋巴结直径与Ⅰb区淋巴结肿大呈正相关关系。Logistic多因素分析结果显示,仅
Ⅱ区淋巴结直径具有统计学意义(P=0.013)。结论鼻咽癌Ⅰb区淋巴结肿大与同侧Ⅱ区淋巴结大小呈显著正相关关系。
Abstract:
Objective To analyze the risk factors for level Ib lymph node enlargement on CT in patients with nasopharyngeal
carcinoma (NPC) and provide clinical evidence for defining the indications of prophylactic level Ib irradiation. Methods A
total of 435 newly diagnosed NPC patients receiving radiotherapy in Nanfang Hospital in the past 2 years were enrolled in this
analysis. The correlations were analyzed with Logistic regression between level Ib lymphadenopathy and the clinical risk
factors including T stage, N stage, diameter of level II lymph nodes, submandibular gland involvement, nasal cavity
involvement, oropharyngeal involvement, and involvement of 4 or more lymphatic drainage regions. Results Univariate
analysis showed that level Ib lymphadenopathy were positively correlated with N stage (P=0.023), submandibular gland
involvement (P=0.045), and level II lymph node diameter (P<0.001). Multivariate Logistic regression analysis suggested a
significant correlation only between the diameter of the level II lymph nodes and level Ib lymphadenopathy (P=0.013).
Conclusion Level Ib lymphadenopathy is positively correlated with the size of ipsilateral level II lymph nodes in NPC
patients.

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更新日期/Last Update: 1900-01-01