[1]刘丹青,王庆军,蔡剑鸣,等.高分辨3D黑血磁共振定量评价颈动脉粥样硬化斑块[J].南方医科大学学报,2013,(03):365.
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高分辨3D黑血磁共振定量评价颈动脉粥样硬化斑块()
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《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2013年03期
页码:
365
栏目:
出版日期:
2013-03-15

文章信息/Info

Title:
Quantitative measurement of carotid atherosclerotic plaque by high-resolution threedimensional black-blood magnetic resonance imaging
作者:
刘丹青王庆军蔡剑鸣蔡幼铨王勇韩旭
关键词:
高分辨黑血磁共振成像技术颈动脉粥样硬化斑块
Keywords:
high-resolution black-blood magnetic resonance imaging carotid atherosclerosis plaques
摘要:
目的通过与高分辨2D黑血磁共振成像技术比较,评价3D黑血磁共振成像(3D-BB-MRI)对颈动脉粥样硬化斑块定量分
析的价值。方法40例患者进行颈动脉常规轴位2D-BB-MRI及斜矢状位3D-BB-MRI扫描。对斜矢状位3D-BB-MRI原始图像
进行轴位重建。对于每个测量对象(单侧颈动脉),由两名有经验的放射科医师在2D-BB-MRI图像上共同找出其斑块测量的兴
趣层面,以此进行3D-BB-MRI轴位重建图像与2D-BB-MRI图像的匹配。对该侧颈动脉分别进行斑块厚度、管腔狭窄程度、管
腔面积、总血管面积的测量及管壁面积和标准化管壁指数的计算,并分析所有数据。结果在评估斑块厚度、管腔狭窄程度、管
腔面积、总血管面积、管壁面积及标准化管壁指数方面,2D-BB-MRI与3D-BB-MRI轴位重建图像的测量差异无统计学意义(P>
0.05),两者呈较强的相关性(r>0.9)。Bland-Altman 图显示对于测量斑块厚度、管腔面积、总血管面积,2D-BB-MRI 与
3D-BB-MRI两种方法具有良好的一致性。结论3D-BB-MRI和2D-BB-MRI对于定量评价颈动脉粥样硬化斑块方面无明显差
异;3D-BB-MRI具有任意角度重建图像、灵活显示管壁及斑块情况的特点,我们认为3D-BB-MRI对于颈动脉粥样硬化成像较
2D-BB-MRI具有更好的发展前景。
Abstract:
Objective To assess the value of high-resolution three-dimensional black-blood magnetic resonance imaging
(3D-BB-MRI) in quantitative measurement of carotid atherosclerotic plaque by comparison with two-dimensional black-blood
magnetic resonance imaging (2D-BB-MRI). Methods Forty patients were scanned with routine 2D and oblique-sagittal
3D-BB-MRI. The original oblique-sagittal 3D images were reformatted to an axial 2D-like dataset. Two experienced radiologists
identified the interested slice in consensus for every patient (unilateral carotid artery) in 2D-BB-MRI images and matched the
axial reformatted 3D images with 2D black-blood images. Plaque thickness (PT), lumen area (LA) and total vessel area (TVA)
were measured, and lumen stenosis (LS) and normalized wall index (NWI) were calculated. Results There was no
measurement difference between 2D-BB-MRI and reformatted 3D-BB-MRI (P>0.05), and these two methods had a good
correlation (r>0.9). The Bland-Altman chart showed that 2D-BB-MRI and 3D-BB-MRI were in good agreement in the
measurement of PT, LA and TVA. Conclusion 3D-BB-MRI and 2D-BB-MRI have no obvious difference in quantitative
measurement of the carotid plaques. 3D-BB-MRI can demonstrate the vessels and plaques by multiplanar reconstruction and
thus have better performance in evaluating carotid atherosclerosis compared with 2D-BB-MRI.

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更新日期/Last Update: 1900-01-01