[1]刘东,唐斌,吴家清,等.肾脏移植术后巨细胞病毒感染并发急性胰腺炎的临床分析[J].南方医科大学学报,2005,(08):1049-1050.
 LIU Dong,TANG Bin,WU Jia-qing,et al.Cytomegalovirus infection accompanied with acute pancreatitis after kidney transplantation[J].Journal of Southern Medical University,2005,(08):1049-1050.
点击复制

肾脏移植术后巨细胞病毒感染并发急性胰腺炎的临床分析()
分享到:

《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2005年08期
页码:
1049-1050
栏目:
出版日期:
2005-08-01

文章信息/Info

Title:
Cytomegalovirus infection accompanied with acute pancreatitis after kidney transplantation
作者:
刘东 唐斌 吴家清 黎程 蒙善东
广东省第二人民医院肾脏移植科, 广东, 广州, 510317
Author(s):
LIU Dong TANG Bin WU Jia-qing LI Cheng MENG Shan-dong
Department of Kidney Transplantation, Second People’s Hospital of Guangdong Province, Guangzhou 510317, China
关键词:
肾脏移植急性胰腺炎巨细胞病毒
Keywords:
kidney transplantationacute pancreatitishuman cytomegalovirus
分类号:
R699.2
摘要:
目的 研究治疗肾脏移植术后巨细胞病毒感染并发急性胰腺炎的方法。方法 顾性分析了5例肾脏移植术后急性胰腺炎病人的临床资料。结果 移植术后急性胰腺炎的发病率为2.3%(5/217)。5例均合并活动性巨细胞病毒感染。其中3例同时伴有高脂血症,2例出现肝功能异常。5例患者中,治愈3例,死亡2例。在死亡的2例中,1例为巨细胞病毒性间质性肺炎呼吸衰竭合并出血坏死性胰腺炎,另1例为活动性人巨噬细胞病毒感染爆发性肝功能衰竭合并出血坏死性胰腺炎。结论 脏移植术后急性胰腺炎可以由多种因素诱发,但与巨细胞病毒感染的关系更为密切,早期诊断和治疗是降低死亡率的关键。
Abstract:
Objective To explore the prevention and management of human cytomegalovirus (HCMV) infection accompanied with acute pancreatitis after kidney transplantation. Methods and Results A retrospective analysis of 5 patients with acute pancreatitis after kidney transplantation was conducted. The incidence of acute pancreatitis after kidney transplantation was 2.3% (5/217). All the 5 cases were complicated by active HCMV infection, 3 of which had hyperlipemia and 2 had liver dysfunction. Three cases were finally cured while the other 2 died, one of which was due to respiration failure arising from HCMV interstitial pneumonia accompanied with hemorrhagic necrotizing pancreatitis, and the other due to fulminating liver function failure because of active HCMV infection accompanied with hemorrhagic necrotizing pancreatitis. Conclusion Active HCMV infection is the most important factor responsible for acute pancreatitis, and early diagnosis and treatment are crucial to lower mortality rate.

参考文献/References:

[1] Asztalos L, Kincses Z, Berczi C, et al. Acute pancreatitis after kidney transplantation[J]. Magy Seb, 2004, 54(2): 91-4.
[2] 吴阶平,裘法祖,黄家驷.外科学[M].第6版,北京:人民卫生出版社,1999.1302.
[3] Slakey DP, Johnson CP, Cziperle DJ, et al. Management of severe pancreatitis in renal transplant recipients[J]. Ann Surg, 1997, 224:217-9.
[4] Sinha S, Jha R, Lakhtakia S, et al. Acute pancreatitis following kidney transplantation-role of viral infections[J]. Clin Transplant,2003, 17: 32-6.
[5] Schmid SW, Uhl W, Steinle A, et al. Human pancreas-specific protein-A diagnostic and prognostic marker inacute pancreatitis and pancreas transplantation[J]. Int J Pancreatol, 1996, 19: 165-8.

相似文献/References:

[1]陆婷,程兴利.急性胰腺炎72例误诊分析[J].南方医科大学学报,2004,(04):374.
[2]陈学清,姜泊,宋于刚,等.早期生长反应因子-1和组织因子在大鼠胰腺炎组织中的表达[J].南方医科大学学报,2004,(11):1245.
 CHEN Xue-qing,JIANG Bo,SONG Yu-gang,et al.Expressions of early growth response 1 and tissue factor in caerulein-induced acute pancreatitis tissues in rats[J].Journal of Southern Medical University,2004,(08):1245.
[3]于立新,叶俊生,邓文锋,等.腹部多器官联合移植的围手术期处理[J].南方医科大学学报,2005,(02):165.
 YU Li-xin,YE Jun-sheng,DENG Wen-feng,et al.Perioperative management of multiorgan transplantation[J].Journal of Southern Medical University,2005,(08):165.
[4]陈焕伟,崔伟珍,王军华,等.介入性超声在重症急性胰腺炎治疗中的价值[J].南方医科大学学报,2005,(10):1316.
 [J].Journal of Southern Medical University,2005,(08):1316.
[5]潘晓鸣,薛武军,刘林娟,等.西北地区开展公民心脏死亡后捐献肾脏移植的报告[J].南方医科大学学报,2014,(03):414.
[6]汪俏妹,罗明武,肖冰.红细胞分布宽度评估急性胰腺炎严重程度的价值[J].南方医科大学学报,2017,(07):993.

备注/Memo

备注/Memo:
收稿日期:2005-5-19。
作者简介:刘东(1963-),男,1999年毕业于中山医科大学,博士,副主任医师,电话:020-84179986
更新日期/Last Update: 1900-01-01