[1]肖耀军,郑少斌,谭万龙,等.保留肾单位手术治疗早期小肾癌21例临床分析[J].南方医科大学学报,2005,(03):357-359.
 XIAO Yao-jun,ZHENG Shao-bin,TAN Wan-long,et al.Nephron-sparing surgery for small renal cell carcinoma: clinical analysis of 21 cases[J].,2005,(03):357-359.
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保留肾单位手术治疗早期小肾癌21例临床分析()
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《南方医科大学学报》[ISSN:/CN:]

卷:
期数:
2005年03期
页码:
357-359
栏目:
出版日期:
2005-03-01

文章信息/Info

Title:
Nephron-sparing surgery for small renal cell carcinoma: clinical analysis of 21 cases
作者:
肖耀军 郑少斌 谭万龙 陈彤 齐桓 邵志强 姜耀东 吴芃 张辉见
南方医科大学南方医院泌尿外科, 广东, 广州, 510515
Author(s):
XIAO Yao-jun ZHENG Shao-bin TAN Wan-long CHEN Tong QI Huan SHAO Zhi-qiang JIANG Yao-dong WU Peng ZHANG Hui-jian
Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
关键词:
肾肿瘤保留肾单位手术
Keywords:
kidney neoplasmsnephron-sparing surgery
分类号:
R69
摘要:
目的 探讨保留肾单位手术治疗早期小肾癌的临床效果。方法 1999年4月~2004年3月,行保留肾单位手术治疗小肾癌21例,其中孤立肾1例,对侧肾有病变或肾功能受损3例,对侧肾正常17例。肿瘤直径1.5~6.0 cm,平均直径2.8cm;其中对侧肾正常者直径均<4cm,平均2.5cm;对侧肾有病变或受损者平均直径为4.2cm。TNM分期:T1期16 例,T2期4 例,T3期1例。4例行肿瘤剜除术,10例行肾极切除术,7例行肿瘤楔形切除术。结果 21例随访7~66个月,平均随访40.8个月。1例3年后发现右肺及纵隔转移,1例术后27月因慢性肾小球肾炎接受透析治疗。其余19例未见并发症及肿瘤局部复发。结论 保留肾单位手术是早期局限性肾癌的安全有效治疗方法,可作为治疗对侧肾正常直径<4cmT1~T2期局限性肾癌的金标准。
Abstract:
Objective To evaluate the clinical effects of nephron-sparing surgery in patients with early-stage small renal cell carcinoma.Methods Nephron-sparing surgery was performed in 21 patients with renal cell carcinoma including 1 with solitary kidney, 3 with unilateral tumor and contralateral renal compromise, and 17 with unilateral tumor and normal contralateral kidney. The diameter of the tumors ranged from 1.5 to 6.0cm, with a mean of 2.8cm. The tumor diameter in 17 patients with normal contralateral kidney was less than 4cm (mean 2.5 cm) and the average diameter in 4 patients with contralateral renal compromise was 4.2 cm. Sixteen cases were in stage T1,4 in stage T2, and 1 in stage T3. Of the 21 patients, 4 underwent tumor enucleation, 10 polar nephrectomy and 7 wedge resection.Results All patients were followed up for an average of 40.8 months (7 to 66 months). One patient suffered a right lung and mediastinum metastasis 3 years after the surgery later and 1 with chronic glomerulonephritis required dialysis 27 months after the operation. No surgical complication or local recurrence were found in other patients.Conclusion As a safe and effective therapy for early-stage small renal cell carcinoma, nephron-sparing surgery can be considered as the gold-standard therapy for patients with lesions less than 4cm in T1 and T2 stages of localized unilateral tumor with normal contralateral kidney.

参考文献/References:

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[6] 陈斌,邢金春,陈实新,等.保留肾单位手术治疗肾肿瘤18例分析[J].临床外科杂志(J Clin Surg),2003,11(1):35-6.
[7] Martorana G,Lupo S,Brunocilla E,et al. Role ofnephron sparing surgery in the treatment of centrally located renal tumors [J]. Arch Ital Urol Androl,2004,76(2):51-5.
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备注/Memo

备注/Memo:
收稿日期:2004-11-2。
作者简介:肖耀军(1974- ),男,南方医科大学在读硕士研究生,电话:13543452658,E-mail:xyj9882002@sina.com
更新日期/Last Update: 1900-01-01