[1]肖文星,宾建平,尚华.血脂水平对无症状高血压患者ST-T改变的影响[J].南方医科大学学报,2004,(04):470-471.
 XIAO Wen-xing,BIN Jian-ping,SHANG Hua.Effects of blood lipid levels on ST-T segment in asymptomatic hypertensive patients[J].,2004,(04):470-471.
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血脂水平对无症状高血压患者ST-T改变的影响()
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《南方医科大学学报》[ISSN:/CN:]

卷:
期数:
2004年04期
页码:
470-471
栏目:
出版日期:
2004-04-01

文章信息/Info

Title:
Effects of blood lipid levels on ST-T segment in asymptomatic hypertensive patients
作者:
肖文星1 宾建平1 尚华2
1. 第一军医大学南方医院心内科, 广东, 广州, 510515;
2. 第一军医大学南方医院康复理疗科, 广东, 广州, 510515
Author(s):
XIAO Wen-xing1 BIN Jian-ping1 SHANG Hua2
1. Department of Cardiology, First Military Medical University, Guangzhou 510515, China;
2. Department of Rehabilitation, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China
关键词:
高血压ST-T改变血脂胆固醇
Keywords:
hypertentionabnormal ST-Tblood lipids cholesterol
分类号:
R541.3
摘要:
目的 探讨无症状高血压患者ST-T改变的影响因素。方法 以无症状高血压患者为研究对象,按心电图表现分为ST-T改变组(28例)和无ST-T改变组(20例),检测两组患者的血糖、血脂水平。结果 与无ST-T改变组相比,ST-T改变者血清总胆固醇水平明显增高,而高密度脂蛋白水平则明显降低(P<0.05),其他检测指标在两组无显著性差异。结论 在血脂正常的无症状高血压患者中,相对较高的总胆固醇水平促使或加重心肌缺血,而高密度胆固醇对心肌损害起着保护作用。
Abstract:
Objective To identify the factors affecting ST-T segment in asymptomatic hypertensive patients. Methods The asymptomatic patients with hypertention were divided into abnormal ST-T group (n=28) and normal ST-T group (n=20), in whom the serum levels of glucose, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), very-low-density lipoprotein cholesterol (VLDL) were measured. Results Com-pared with patients with normal ST-T segment, patients with abnormal ST-T segment had significantly higher serum levels of TC, but significantly lower HDL. The serum levels of glucose, TG, LDL, VLDL differed little between the 2 groups of pa-tients. Conclusion In asymptomatic patients with hypertension, higher serum TC level may cause or worsen ischemic my-ocardial damage, for which HDL plays a protective role.

参考文献/References:

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[2] Law MR, Wald NJ, Thompson SG. By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease[J]? BMJ, 1994, 308: 367-72.
[3] Law MR. Lowering heart disease risk with cholesterol reduction: evidence firom observational studies and clinical trials[J]. Eur Heart J,1999, (suppl S): S3-8.
[4] ATP Ⅲ Final Report: Ⅱ. Rationale for intervention. Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel) Ⅲ)[J]. Circulation, 2002, 106:3163-223.
[5] Wilkinson IB, Prasad K, Hall IR, et al. Increased central pulse pressure and augmentation index in subjects with hypercholesterolemia[J]. J Am Coll Cardiol, 2002, 39(6): 1005-11.
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备注/Memo

备注/Memo:
收稿日期:2003-9-16。
作者简介:肖文星(1969-),1993年毕业于苏州医学院,本科,现为南方医院心内科在读硕士,E-mail:xwx@fimmu.com.
更新日期/Last Update: 1900-01-01