[1]龙宝军,陈柯,张栋杰,等.酪蛋白磷酸肽-非结晶型磷酸钙溶液预防牙釉质脱矿的实验研究[J].南方医科大学学报,2014,(03):430.
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酪蛋白磷酸肽-非结晶型磷酸钙溶液预防牙釉质脱矿的实验研究()
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《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2014年03期
页码:
430
栏目:
出版日期:
2014-03-15

文章信息/Info

Title:
Effect of casein osphopeptide-amorphous calcium phosphate solution in preventing
enamel demineralization
作者:
龙宝军陈柯张栋杰李云鹏
关键词:
酪蛋白磷酸肽一非结晶型磷酸钙脱矿牙釉质氟化物扫描电镜
Keywords:
casein osphopeptide-amorphous calcium phosphate demineralization enamel fluoride scanning electron microscopy
摘要:
目的观察GC护牙素[酪蛋白磷酸肽一非结晶型磷酸钙(CPP-ACP)溶液]预防脱矿液对牙釉质脱矿的效果。方法选取
68个因正畸需要拔除的未患龋的前磨牙,均未见牙体表面缺损,彻底清洗后切割成釉质面,打磨成平滑面,保留釉质窗口面,随
机分成4组,分别置于0.2% NaF、2% NaF、CPP-ACP、蒸馏水中浸泡7 d,置于脱矿夜中浸泡7 d。进行扫描电镜照射,观察釉质
层变化,同时采用电子探针检测仪检测脱矿后釉质层硬组织钙、磷、镁3 种元素的分布状况,并进行统计学分析。结果0.2%
NaF、2% NaF、CPP-ACP溶液组牙釉质脱矿率均低于蒸馏水组,且釉质层中钙、磷的含量明显高于蒸馏水组,而镁元素的含量4
组无统计学差异,说明0.2% NaF、2% NaF、CPP-ACP均对预防牙釉质脱矿有一定的保护作用。结论5% CPP-ACP是一种预防
牙釉质脱矿的安全有效的措施,其作用与0.2% NaF组相似。
Abstract:
Objective To evaluate the effects of casein osphopeptide-amorphous calcium phosphate (CPP-ACP) in preventing
enamel demineralization. Methods Enamel blocks were prepared from premolars extracted from orthodontic patients. The
specimens were treated for 30 min daily for 7 days with one of the following agents: deionized water (negative control),
CPP-ACP paste, and NaF solutions (positive controls) (0.2% and 2%). After the treatments, the specimens were immersed in a
demineralizing solution (pH 4.5) for 7 days. The morphology and depth of the lesion were observed using scanning electron
microscopy, and the content of Ca, P, Mg in the demineralized enamel was measured by electron probe micro-analyzer.
Results The demineralization rates in all the treatment groups were significantly smaller than those in the control group after 7
days of demineralization. Conclusion The application of CPP-ACP to the enamel surfaces can inhibit enamel demineralization
with an equivalent effect to 0.2% NaF.
更新日期/Last Update: 1900-01-01