[1]汪晶晶,陈韵岱,王晶,等.双脉冲多普勒超声心动图技术测量TE-e’评估冠心病患者左心室舒张功能[J].南方医科大学学报,2014,(03):349.
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双脉冲多普勒超声心动图技术测量TE-e’评估冠心病患者左心室舒张功能()
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《南方医科大学学报》[ISSN:/CN:]

卷:
期数:
2014年03期
页码:
349
栏目:
出版日期:
2014-03-15

文章信息/Info

Title:
Evaluation of left ventricular diastolic function by TE-e’ measurement using dual Doppler
echocardiography in coronary heart disease patients with preserved systolic function
作者:
汪晶晶陈韵岱王晶智光穆洋徐勇
关键词:
组织多普勒成像技术冠心病左室舒张功能左室舒张末压力双脉冲多普勒技术
Keywords:
Doppler tissue imaging coronary heart disease left ventricular diastolic function left ventricular end-diastolicpressure dual Doppler echocardiography
摘要:
目的探讨双脉冲多普勒超声心动图技术测量舒张早期二尖瓣血流E波开始时间与舒张早期二尖瓣瓣环e’波开始时间差
值TE-e’,评估TE-e’诊断左心室舒张功能不全准确性。方法连续入组冠心病患者77例,所有患者均行冠脉造影,心导管测量左心
室舒张末压力(LVEDP);双脉冲多普勒技术测量舒张早期二尖瓣血流峰值速度E与舒张早期二尖瓣瓣环峰值速度e’,计算E/e’
与TE-e’,评估左心室舒张末压力与TE-e’相关性及E/e’、TE-e’与TE-e’联合E/e’,诊断左心室舒张末功能不全[指左心室舒张末期压力
≥12 mmHg(1 mmHg=0.133 kPa)]的准确性。结果1、左心室舒张末压(LVEDP)与TE-e’,E/e’相关性分别为r=0.42和r=0.79,P<
0.001;2、TE-e’≥38 ms时,诊断左心室舒张功能不全的敏感性为54%,特异性为79%,ROC曲线下面积0.71。E/e’≥9.2时,诊断左
心室舒张功能不全敏感性为74%,特异性为81%,ROC曲线下面积0.87;3、联合E/e’≥9.2,TE-e’≥38 ms诊断左心室舒张功能不全敏
感性为100%,特异性为62%,ROC曲线下面积0.96。结论双脉冲多普勒技术测量TE-e’为评估左心室舒张功能不全的有效指
标,联合E/e’能够提高诊断左心室舒张功能不全的准确性。
Abstract:
Objective To evaluate the accuracy of the time interval between the onset of early transmitral flow velocity (E) and
that of early diastolic mitral annular velocity (e’) (TE-e’) measured by dual Doppler echocardiography in the diagnosis of
diastolic dysfunction. Methods Seventy-seven coronary heart disease patients with preserved systolic function underwent a
echocardiographic study. Early transmitral flow velocity E and early diastolic mitral annular velocity e’ were simultaneously
recorded by dual Doppler echocardiography. The E/e’ and TE-e’ were calculated and compared with the left ventricular end
diastolic pressure (LVEDP), which was measured invasively. The validity of TE-e’, E/e’ and their combination was analyzed in
estimating left ventricular dysfunction (LVEDP ≥12 mmHg). Results The single-beat E/e’ and TE-e’ were correlated with the
LVEDP (r=0.79 and 0.42, respectively, P<0.001). Receiver-operating characteristic analysis showed that the optimal cut-off for
TE-e’ was 38 ms (sensitivity 54%, specificity 79%, AUC 0.71) and that for E/e’ was 9.2 (sensitivity 74%, specificity 81%, AUC 0.87)
for diagnosis of left ventricular diastolic dysfunction. The combined cut-offs of TE-e’ ≥38 ms and E/e’ ≥9.2 had a sensitivity of
100% and a specificity of 62% in diagnosing left ventricular diastolic dysfunction with an AUC of 0.96. Conclusion In patients
with coronary heart disease, the simultaneous recording of TE-e’ by dual Doppler echocardiography can accurately estimate
diastolic dysfunction, and its combination with E/e’ can further improve the diagnostic accuracy.

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更新日期/Last Update: 1900-01-01