[1]苏薇薇,赵洁,林敬明.高效液相色谱法测定水母雪莲中东莨菪内酯、伞形花内酯的含量[J].南方医科大学学报,2005,(01):119-120.
 SU Wei-wei,ZHAO Jie,LIN Jing-ming.Determination of scopoletin and umbelliferone contents in Saussurea medusa Maxim by high-performance liquid chromatography[J].,2005,(01):119-120.
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高效液相色谱法测定水母雪莲中东莨菪内酯、伞形花内酯的含量()
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《南方医科大学学报》[ISSN:/CN:]

卷:
期数:
2005年01期
页码:
119-120
栏目:
出版日期:
2005-01-01

文章信息/Info

Title:
Determination of scopoletin and umbelliferone contents in Saussurea medusa Maxim by high-performance liquid chromatography
作者:
苏薇薇1 赵洁2 林敬明3
1. 南方医科大学研究生大队, 广东广州510515;
2. 南方医科大学南方医院药材科, 广东广州510515;
3. 南方医科大学珠江医院药材科, 广东广州510282
Author(s):
SU Wei-wei1 ZHAO Jie2 LIN Jing-ming3
1. Postgraduate Division, Southern Medical University, Guangzhou 510515, China;
2. Department of Pharmaceutics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;
3. Department of Pharmaceutics, Zhujiang Hospital, Southern Medic
关键词:
水母雪莲东莨菪内酯伞形花内酯高效液相色谱
Keywords:
Saussurea medusa Maximscopletinumbelliferone
分类号:
O657.7+2
摘要:
用高效液相色谱法测定水母雪莲中东莨菪内酯、伞形花内酯的含量。色谱柱采用Merck Lichrospher100RP-18e(250mm×4.0mm,5μm);流动相采用甲醇-四氢呋喃水溶液;检测波长为346nm。东莨菪内酯平均回收率为100.07%,RSD为1.42%;伞形花内酯平均回收率为99.41%,RSD为2.06%。本法简单、快速、准确,可用于水母雪莲的质量控制。
Abstract:
Objective To investigate the therapeutic effect of photodynamic therapy (PDT) combined with interstitial chemo-therapy on gliomas after microsurgery. Methods Twenty-eight patients with glioma received microsurgery for glioma resection as much as possible, during which PDT was carried out and an Ommaya bursa implanted into the cavity left by the resected tumor. PDT was performed again 24 h after the operation and carmustine injected into the Ommaya bursa for interstitial chemotherapy at the different time after the operation. The follow-up study lasted for 2 years. Results Two of the 28 patients had relapse of glioma within 1 year after the operation, with the 1-year survival rate of 89.3% (25/28) and 2-year survival rate of 65.7% (17/28). Conclusions PDT combined with interstitial chemotherapy following microsurgery provides a safe and effective treatment of glioma, which can inhibit glioma growth, decrease the recurrence rate, prolong the patients’ survival and improve their quality of live.

参考文献/References:

[1] 卫生部药典委员会.中华人民共和国卫生部药品标准(藏药第一册)[M].北京:化学工业出版社,1995.94.
[2] 杨雪梅,刘旭,严轶琛,等.HPLC测定S-西酞普兰[J].第一军医大学学报,2004,24(6):716-8.Yan XM, Liu S, Yan YC, et al. Content determination of S-citalopram by chiral high-performance liquid chromatography[J].J First Mil Med Univ/Di Yi Jun Yi Da Xue Xue Bao, 2004, 24(6):716-8.

备注/Memo

备注/Memo:
收稿日期:2004-2-16。
作者简介:苏薇薇(1959- ),女,博士研究生,电话:020-84110808
更新日期/Last Update: 1900-01-01