[1]马涛,姚学清,林锋,等.结直肠癌患者手术前后营养及免疫功能的对照观察[J].南方医科大学学报,2005,(01):76-78.
 MA Tao,YAO Xue-qing,LIN Feng,et al.Changes in nutritional status and immune function in patients with colorectal cancer after operation[J].Journal of Southern Medical University,2005,(01):76-78.
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结直肠癌患者手术前后营养及免疫功能的对照观察()
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《南方医科大学学报》[ISSN:1673-4254/CN:44-1627/R]

卷:
期数:
2005年01期
页码:
76-78
栏目:
出版日期:
2005-01-01

文章信息/Info

Title:
Changes in nutritional status and immune function in patients with colorectal cancer after operation
作者:
马涛1 姚学清2 林锋2 钟世镇3
1. 汕头大学第一附属医院普外科, 广东汕头515041;
2. 广东省人民医院胃肠外科, 广东广州510080;
3. 南方医科大学临床解剖学研究所, 广东广州510515
Author(s):
MA Tao1 YAO Xue-qing2 LIN Feng2 ZHONG Shi-zhen3
1. Department of General Surgery, First Affiliated Hospital of Shantou University, Shantou 515041, China;
2. Department of Gastrointestinal Surgery, People’s Hospital of Guangdong Province, Guangzhou 510080, China;
3. Institute of Clinical Anatomy,
关键词:
结直肠癌/外科学营养免疫功能
Keywords:
colorectal cancer/surgerynutritionimmune function
分类号:
R459.3
摘要:
目的 探讨结直肠癌患者手术前后的营养及免疫功能临床指标。方法 随机检测40例结直肠癌患者术前、术后营养和免疫指标并与对照组比较。结果 结直肠癌患者术后IgM、IgG、白蛋白、前白蛋白显著低于术前(P<0.05),而对照组良性肿瘤手术患者手术前后指标无显著差异。结论 结直肠癌术后营养及免疫功能显著差于术前。
Abstract:
Objective To evaluate the changes in the nutritional status and immune function in patients with colorectal cancer after operation. Methods The indexes of the nutritional status and immune function were measured in 40 patients with colorectal cancer before and after operation and compared with the control group. Results The levels of IgM, IgG, prealbumin and transferrin were lowered after operation in these colorectal cancer patients (P<0.05), but no significant difference was noted after operation in the control group. Conclusion The nutritional status and immune function in colorectal cancer patients obviously deteriorate after operation.

参考文献/References:

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[3] Soreide O, Norstein. Local recurrence after operative treatment of rectal carcinoma: A strategy for chance [J]. J Am Coil Surg, 1997,184: 84-92.
[4] Du WB, Chia KS, Sankaranarayanan R. Population-based survival analysis of colorectal cancer patients in Singapore, 1968-1992 [J].Int J Cancer, 2002, 99(3): 460-5.
[5] Vander Pompe G, Antoni MH, Visser A, et al. Effect of mild acute stress on immune cell distribution and natural killer cell activity in breast cancer patients[J]. Biol Psychol, 1998, 48(1): 21-5.
[6] Yoon SJ, Heo DS, Kang SH, et al. Natural killer cell activity depression in peripheral blood and ascites from gastric cancer patients with high TGF-beta 1 expression [J]. Anticancer Res, 1998, 18 (3A):1591-6.
[7] Carson WE, Parihar R, Lindemann MJ, et al. Interleukin-2 enhances the natural cell response to Herceptin-coated Her2/neu-positive breast cancer cells[J]. Eur J Immunol, 2001, 31(10): 3016-25.
[8] Ishigami S, Natsugoe S, Tokuda K, et al. Clinical impact of intratumoral natural killer cell and dendritic cell infiltration in gastric cancer[J]. Cancer Lett, 2000, 159(1): 103-8.
[9] Cooley S, Burns LJ, Repka T, et al. Natural killer cell cytotoxicity of breast cancer targets is enhanced by two distinct mechanisms of antibody-dependent cellular cytotoxicity against LFA -3 and HER2/neu[J]. Exp Hematol. 1999, 27(10): 1533-41.
[10] Dunn J, Lynch B, Aitken J, et al. Quality of life and colorectal cancer: a review[J]. Aust J Health, 2003, 27(1): 41-53.

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备注/Memo

备注/Memo:
收稿日期:2004-5-12。
基金项目:广东省科技攻关项目(99B06703G)
作者简介:马涛(1959- ),1984年毕业于第四军医大学,副教授,副主任医师,电话:0754-8899935
通讯作者:姚学清,电话:020-83827812-12310
更新日期/Last Update: 1900-01-01